R-421A Refrigerant 25 lb

R-421A Refrigerant 25 lb

 (1837 Reviews)
$59.99
$59.99 $180.00
SAVE 66% Sold out
 
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R-421A Refrigerant 25 lb

R-421A Refrigerant 25 lb

$59.99
$59.99 $180.00
SAVE 66% Sold out
Refrigerant R-421A

Refrigerant R-421A is a non-ozone-depleting HFC blend engineered as a direct replacement for R-22 in existing systems. It delivers reliable performance while allowing a smooth transition away from ozone-depleting refrigerants.

One of the key advantages of R-421A is its broad lubricant compatibility. It can be used with mineral oil, alkylbenzene (AB), or polyolester (POE) oils, helping reduce retrofit complexity and minimizing system modifications.

R-22 Replacement
Non-Ozone Depleting
Multi-Oil Compatible
ARI-700 Certified
Applications
  • Residential and commercial air conditioning systems
  • Medium-temperature refrigeration
  • High-temperature refrigeration applications
  • Commercial and industrial cooling systems
Product Quality & Assurance

When you purchase from Refrigerants Depot, you receive brand new, 100% virgin refrigerants that meet or exceed ARI-700 purity standards. Every cylinder is quality-tested to ensure dependable performance and system safety.

Shipping Information
All orders are shipped via UPS Hazmat Ground or approved freight services in full compliance with DOT regulations.

Most orders ship within 1 business day for fast and reliable delivery.

  • Great customer service and top-notch refrigerants! The R-410A worked perfectly for my HVAC system. Fast shipping and exactly as described. I'll definitely be ordering again!

    John M. ⭐⭐⭐⭐⭐

  • Ordered R-22 and R-134A cylinders for a big project. Everything arrived on time, well-packaged, and at the best price I found online. Highly recommend for any HVAC professional!

    Carlos D. ⭐⭐⭐⭐⭐

  • Really impressed with the quality and the free shipping. The R-404A refrigerant was exactly what I needed. This is now my go-to supplier for all my refrigerant needs.

    Emily R. ⭐⭐⭐⭐⭐
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    Why Choose Refrigerant Depot?

    Factory-direct quality, unbeatable prices, and fast shipping nationwide.

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    Factory Direct Pricing

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    All orders ship free across the United States — no minimum order required.

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    High-Quality Refrigerants

    Every cylinder is certified and tested to meet HVAC industry standards.

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    Easy Returns & Support

    Not satisfied? Our team is ready to help with hassle-free returns and expert support.

    Limited stock. Get it before prices rise again.

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      Certified Quality

      Every refrigerant cylinder is tested and meets all HVAC industry standards.

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      Factory Direct Prices

      We cut out the middleman so you always get the lowest price guaranteed.

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      Fast & Free Shipping

      All U.S. orders ship free — no minimum required. Most orders arrive in 3-5 days.

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      What Our Customers Say

      • Best Price Online!

        I've been using R-410A from Refrigerant Depot for months. Reliable quality, fast delivery, and the best price I've found anywhere. Definitely my go-to supplier!

        John M.

      • Fast Shipping & Great Quality

        Ordered R-22 and R-134A for a big project. Everything arrived on time, well-packaged, and exactly as described. The free shipping was a great bonus!

        Carlos D.

      • Highly Recommend!

        Great customer service and top-notch refrigerants. The R-407C worked perfectly for my system. I was impressed with the quality and I'll definitely order again!

        Emily R.

        Customers are saying

        4.80 ★ (80)
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